Novel Anticoagulants

Apixaban, Dabigatran, Edoxaban, Rivaroxaban

New blood-thinning medicines used to help prevent blood clots from forming. Use depends on other medical conditions. These drugs do not require blood monitoring and are not affected by food. However, it is not recommended for patients who have prosthetic or mechanical heart valves.

Common Dose: APIXABAN (eliquis) or DABIGATRAN (pradaxa) is to be taken 2 times a day with or without food. EDOXABAN (savaysa) is taken once a day with or without food. RIVAROXABAN (xarelto) is taken once a day with the evening meal.

Common Side Effects: Bleeding is the most common side effect. Special Consideration for all Anticoagulants: Let your dentist or other health care providers know that you are taking a blood thinner if you are having surgery or a procedure.

Call your healthcare provider right away if you notice these side effects:

  • Allergic Reaction: Itching or hives, swelling in your face or hands. Tingling in your mouth, throat or legs. Wheezing or trouble breathing.
  • Any unexpected bleeding: gums, nose, heavier menstrual bleeding than normal.
  • Vomiting blood, or vomit that looks like coffee grounds.
  • Red, pink or brown urine or stools.
  • Sudden or severe headache, confusion, or problems with vision, speech, or walking (could be a sign of stroke).
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